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Deciphering The Role of Succinate Dehydrogenase in Drug Discovery: SDH in Drug Discovery by Vaishali Manikrao Patil, Dileep Kumar, Satya P. Gupta

• Deciphering The Role of Succinate Dehydrogenase in Drug Discovery: SDH in Drug Discovery
• Vaishali Manikrao Patil, Dileep Kumar, Satya P. Gupta
• Page: 298
• Format: pdf, ePub, mobi, fb2
• ISBN: 9789819668304
• Publisher: Springer Nature Singapore

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The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and regulation mechanisms to its deficiency and its implications in related disorders. It also encompasses the impact of SDH in obstructive pulmonary disorders, discussing its potential contributions and implications. It explores the design and development of SDH inhibitors as potent agent against fungal infections. It further examines the relationship between SDH mutations and cancer development, linking genetic alterations to tumorigenesis. The book focuses on therapeutic strategies and highlights the role of SDH in managing gastrointestinal tumors, neurodegenerative disorders, and aging-related diseases. It navigates through the challenges and prospects of utilizing SDH as a target for therapeutic interventions. The book also dives into the diagnostic aspects of SDH defects, elucidating their implications and potential diagnostic investigations. It serves as a comprehensive guide to unravel SDH's functions, dysfunctions, and therapeutic potentials. By amalgamating diverse areas such as enzymology, genetics, pharmacology, and disease management, this book emerges as an invaluable resource for researchers, clinicians, and students alike.

Deciphering the Role of Succinate Dehydrogenase in Drug Discovery
Neurodegenerative Diseases and Succinate Dehydrogenase: A Therapeutics Avenue for Treatment.- Chapter 10. Fungicidal SDH Inhibitors in Agriculture: Regulation .
Deciphering the Role of Succinate Dehydrogenase in Drug .
The book focuses on therapeutic strategies and highlights the role of SDH in managing gastrointestinal tumors, neurodegenerative disorders, and aging-related .
[PDF] Succinate Dehydrogenase, Succinate, and Superoxides - HAL
Nowadays, this theme is experiencing a real revival following the discovery of the role of SDH and succinate in a subset of tumors and cancers .
Succinate dehydrogenase inhibition leads to epithelial .
Succinate dehydrogenase (SDH) is a mitochondrial metabolic enzyme complex involved in both the electron transport chain and the citric acid .
Deciphering the Role of Succinate Dehydrogenase in Drug Discovery
The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and .
Identification and Validation of Novel Drug Targets for the Treatment .
The interplay between the pathways crucial for the parasite, such as pyrimidine biosynthesis, aspartate metabolism, and mitochondrial .
What are SDH2 inhibitors and how do they work? - Patsnap Synapse
Succinate dehydrogenase (SDH) is an essential enzyme in the mitochondrial electron transport chain and the Krebs cycle. By catalyzing the .
[PDF] Abstract - bioRxiv
new avenue for the design and development of novel succinate dehydrogenase inhibitors and . drug discovery with recurrent neural networks.
Deciphering The Role of Succinate Dehydrogenase in Drug .
The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and .
Deciphering the Role of Succinate Dehydrogenase in Dru. - Knygos.lt
in 21 hours The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from .
What are SDH2 modulators and how do they work?
SDH2 modulators work by influencing the activity of the SDH complex. Specifically, SDH2 is part of the enzyme succinate dehydrogenase.
Deciphering The Role of Succinate Dehydrogenase in Drug Discovery
The book explores various aspects of Succinate Dehydrogenase (SDH) (an enzyme crucial for cellular respiration and energy production) from its assembly and .

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